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Methylation-dependent Silencing of CST6 in Primary Human Breast Tumors and Metastatic Lesions
CST6 is a breast tumor suppressor gene that is expressed in normal breast epithelium, but is epigenetically silenced as a consequence of promoter hypermethylation in metastatic breast cancer cell lines. In the current study, we investigated the expression and methylation status of CST6 in primary br...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2007
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2693953/ https://ncbi.nlm.nih.gov/pubmed/17540367 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexmp.2007.03.008 |
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