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Methylation-dependent Silencing of CST6 in Primary Human Breast Tumors and Metastatic Lesions

CST6 is a breast tumor suppressor gene that is expressed in normal breast epithelium, but is epigenetically silenced as a consequence of promoter hypermethylation in metastatic breast cancer cell lines. In the current study, we investigated the expression and methylation status of CST6 in primary br...

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Detalhes bibliográficos
Main Authors: Rivenbark, Ashley G., Livasy, Chad A., Boyd, Courtney E., Keppler, Daniel, Coleman, William B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2693953/
https://ncbi.nlm.nih.gov/pubmed/17540367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexmp.2007.03.008
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