The triple combination of tenofovir, emtricitabine and efavirenz shows synergistic anti-HIV-1 activity in vitro: a mechanism of action study

BACKGROUND: Tenofovir disoproxil fumarate (TDF), emtricitabine (FTC), and efavirenz (EFV) are the three components of the once-daily, single tablet regimen (Atripla) for treatment of HIV-1 infection. Previous cell culture studies have demonstrated that the double combination of tenofovir (TFV), the...

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Detalhes bibliográficos
Main Authors: Feng, Joy Y, Ly, John K, Myrick, Florence, Goodman, Derrick, White, Kirsten L, Svarovskaia, Evguenia S, Borroto-Esoda, Katyna, Miller, Michael D
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2693498/
https://ncbi.nlm.nih.gov/pubmed/19439089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-6-44
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