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Allosterically Coupled Calcium and Magnesium Binding Sites are Unmasked by Ryanodine Receptor Chimeras
We studied cation regulation of wild type ryanodine receptor type 1 ((WT)RyR1), type 3 ((WT)RyR3) and RyR3/RyR1 chimeras (Ch) expressed in 1B5 dyspedic myotubes. Using [(3)H]ryanodine binding to sarcoplasmic reticulum (SR) membranes, Ca(2+) titrations with (WT)RyR3 and three chimeras show biphasic a...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2007
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2693413/ https://ncbi.nlm.nih.gov/pubmed/18096513 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2007.12.058 |
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