Structural and functional consequences of the substitution of glycine 65 by arginine in the N-lobe of human transferrin

The G65R mutation in the N-lobe of human transferrin was created to mimic a naturally occurring variant (G394R) found in the homologous C-lobe. Because Gly65 is hydrogen-bonded to the iron-binding ligand Asp63, it comprises part of the second shell hydrogen bond network surrounding the iron within t...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Mason, Anne B., Halbrooks, Peter J., James, Nicholas G., Byrne, Shaina L., Grady, John K., Chasteen, N. Dennis, Bobst, Cedric E., Kaltashov, Igor A., Smith, Valerie C., MacGillivray, Ross T. A., Everse, Stephen J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
Materias:
Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2693239/
https://ncbi.nlm.nih.gov/pubmed/19219998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi802254x
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares