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Activation-induced non-responsiveness (anergy) limits CD8 T cell responses to tumors
Naïve CD8 T cells respond to signals provided by Ag, costimulation and cytokines by proliferating and differentiating to develop effector functions. Following initial clonal expansion, however, the cells develop activation-induced non-responsiveness (AINR), a form of anergy characterized by an inabi...
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| Główni autorzy: | , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2007
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2693139/ https://ncbi.nlm.nih.gov/pubmed/17656106 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcancer.2007.06.008 |
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