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Detuning CD8 T cells: down-regulation of CD8 expression, tetramer binding, and response during CTL activation

CD8 is critical for T cell recognition of peptide/class I major histocompatability complex ligands, yet is down-regulated during activation of CD8 T cells. We report that loss of CD8 expression early during in vivo responses to vaccinia virus or Listeria monocytogenes (LM) correlates with decreased...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Xiao, Zhengguo, Mescher, Matthew F., Jameson, Stephen C.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Rockefeller University Press 2007
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118473/
https://ncbi.nlm.nih.gov/pubmed/17954566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20062376
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