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ICAM-1 dependent homotypic aggregates regulate CD8 T cell effector function and differentiation during T cell activation()
A hallmark of T cell activation in vitro and in vivo is the clustering of T cells with each other via interaction of the LFA-1 integrin with ICAM-1. The functional significance of these homotypic aggregates in regulating T cell function remains unknown. We used an APC-free in vitro activation system...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3803108/ https://ncbi.nlm.nih.gov/pubmed/23997225 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1201954 |
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