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Fuel specificity of the hepatitis C virus NS3 helicase

The hepatitis C virus (HCV) NS3 protein is a helicase capable of unwinding duplex RNA or DNA. This study uses a newly developed molecular beacon based helicase assay (MBHA) to investigate how nucleoside triphosphates (NTPs) fuel HCV helicase catalyzed DNA unwinding. The MBHA monitors the irreversibl...

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Bibliografske podrobnosti
Main Authors: Belon, Craig A., Frick, David N.
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2692962/
https://ncbi.nlm.nih.gov/pubmed/19332076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.03.059
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