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A Method to Simultaneously Monitor Hepatitis C Virus NS3 Helicase and Protease Activities

The hepatitis C virus NS3 protein contains a N-terminal serine protease and a C-terminal helicase that unwinds RNA or DNA duplexes. The HCV NS3 protein is the target for several antiviral drugs in clinical trials, which inhibit the protease function. A method is reported to simultaneously monitor th...

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Detalhes bibliográficos
Main Authors: Frick, David N., Ginzburg, Olya, Lam, Angela M. I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2838209/
https://ncbi.nlm.nih.gov/pubmed/20225153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-60327-355-8_16
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