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A Method to Simultaneously Monitor Hepatitis C Virus NS3 Helicase and Protease Activities
The hepatitis C virus NS3 protein contains a N-terminal serine protease and a C-terminal helicase that unwinds RNA or DNA duplexes. The HCV NS3 protein is the target for several antiviral drugs in clinical trials, which inhibit the protease function. A method is reported to simultaneously monitor th...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2838209/ https://ncbi.nlm.nih.gov/pubmed/20225153 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-60327-355-8_16 |
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