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Cigarette smoke-induced emphysema in A/J mice is associated with pulmonary oxidative stress, apoptosis of lung cells, and global alterations in gene expression

Cigarette smoking is the major risk factor for developing chronic obstructive pulmonary disease, the fourth leading cause of deaths in the United States. Despite recent advances, the molecular mechanisms involved in the initiation and progression of this disease remain elusive. We used Affymetrix Ge...

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Main Authors: Rangasamy, Tirumalai, Misra, Vikas, Zhen, Lijie, Tankersley, Clarke G., Tuder, Rubin M., Biswal, Shyam
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2692799/
https://ncbi.nlm.nih.gov/pubmed/19286929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.90369.2008
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