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Assessing the role of immuno-proteasomes in a mouse model of familial ALS
The accumulation of protein aggregates is thought to be an important component in the pathogenesis of mutant SOD1 induced disease. Mutant SOD1 aggregates appear to be cleared by proteasomes, at least in vitro, suggesting a potentially important role for proteasome degradation pathways in vivo. G93A...
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| Main Authors: | , , |
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| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
2007
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2692686/ https://ncbi.nlm.nih.gov/pubmed/17482163 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2007.03.024 |
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