Disease Progression in a Transgenic Model of Familial Amyotrophic Lateral Sclerosis Is Dependent on Both Neuronal and Non-Neuronal Zinc Binding Proteins

Mutations in the Cu/Zn superoxide dismutase (SOD1) gene cause one form of familial amyotrophic lateral sclerosis, a progressive disorder of motor neurons leading to weakness and death of affected individuals. Experiments using both transgenic mice expressing mutant SOD1 and SOD1 knock-out mice have...

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Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: Puttaparthi, Krishna, Gitomer, William L., Krishnan, Uma, Son, Marjatta, Rajendran, Bhagya, Elliott, Jeffrey L.
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2002
Fag:
ARTICLE
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6757708/
https://ncbi.nlm.nih.gov/pubmed/12388585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.22-20-08790.2002
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