The heavy metal cadmium induces valosin-containing protein (VCP)-mediated aggresome formation

Cadmium (Cd(2+)) is a heavy metal ion known to have a long biological half-life in humans. Accumulating evidence shows that exposure to Cd(2+) is associated with neurodegenerative diseases characterized by the retention of ubiquitinated and misfolded proteins in the lesions. Here, we report that Cd(...

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Main Authors: Song, Changcheng, Xiao, Zhen, Nagashima, Kunio, Li, Chou-Chi H., Lockett, Stephen J., Dai, Ren-Ming, Cho, Edward H., Conrads, Thomas P., Veenstra, Timothy D., Colburn, Nancy H., Wang, Qing, Wang, Ji Ming
Format: Artigo
Language:Inglês
Published: 2008
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2692476/
https://ncbi.nlm.nih.gov/pubmed/18261755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2007.12.026
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