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Sigma Receptors Suppress Multiple Aspects of Microglial Activation
During brain injury, microglia become activated and migrate to areas of degenerating neurons. These microglia release pro-inflammatory cytokines and reactive oxygen species causing additional neuronal death. Microglia express high levels of sigma receptors, however, the function of these receptors i...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2009
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2692292/ https://ncbi.nlm.nih.gov/pubmed/19031439 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.20802 |
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