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Sigma Receptors Suppress Multiple Aspects of Microglial Activation

During brain injury, microglia become activated and migrate to areas of degenerating neurons. These microglia release pro-inflammatory cytokines and reactive oxygen species causing additional neuronal death. Microglia express high levels of sigma receptors, however, the function of these receptors i...

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Bibliografiske detaljer
Main Authors: Hall Aaron, A., Yelenis, Herrera, Ajmo Craig, T., Javier, Cuevas, Pennypacker Keith, R.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2692292/
https://ncbi.nlm.nih.gov/pubmed/19031439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.20802
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