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Sigma Receptors Suppress Multiple Aspects of Microglial Activation
During brain injury, microglia become activated and migrate to areas of degenerating neurons. These microglia release pro-inflammatory cytokines and reactive oxygen species causing additional neuronal death. Microglia express high levels of sigma receptors, however, the function of these receptors i...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2692292/ https://ncbi.nlm.nih.gov/pubmed/19031439 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.20802 |
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