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Sigma Receptors Suppress Multiple Aspects of Microglial Activation

During brain injury, microglia become activated and migrate to areas of degenerating neurons. These microglia release pro-inflammatory cytokines and reactive oxygen species causing additional neuronal death. Microglia express high levels of sigma receptors, however, the function of these receptors i...

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Hlavní autoři: Hall Aaron, A., Yelenis, Herrera, Ajmo Craig, T., Javier, Cuevas, Pennypacker Keith, R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2692292/
https://ncbi.nlm.nih.gov/pubmed/19031439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.20802
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