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Structural insights into the cooperative binding of SeqA to a tandem GATC repeat

SeqA is a negative regulator of DNA replication in Escherichia coli and related bacteria that functions by sequestering the origin of replication and facilitating its resetting after every initiation event. Inactivation of the seqA gene leads to unsynchronized rounds of replication, abnormal localiz...

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Библиографические подробности
Главные авторы: Chung, Yu Seon, Brendler, Therese, Austin, Stuart, Guarné, Alba
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2009
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2691817/
https://ncbi.nlm.nih.gov/pubmed/19304745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp151
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