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Structural insights into the cooperative binding of SeqA to a tandem GATC repeat

SeqA is a negative regulator of DNA replication in Escherichia coli and related bacteria that functions by sequestering the origin of replication and facilitating its resetting after every initiation event. Inactivation of the seqA gene leads to unsynchronized rounds of replication, abnormal localiz...

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Autors principals: Chung, Yu Seon, Brendler, Therese, Austin, Stuart, Guarné, Alba
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2691817/
https://ncbi.nlm.nih.gov/pubmed/19304745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp151
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