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Structural insights into the cooperative binding of SeqA to a tandem GATC repeat

SeqA is a negative regulator of DNA replication in Escherichia coli and related bacteria that functions by sequestering the origin of replication and facilitating its resetting after every initiation event. Inactivation of the seqA gene leads to unsynchronized rounds of replication, abnormal localiz...

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Détails bibliographiques
Auteurs principaux: Chung, Yu Seon, Brendler, Therese, Austin, Stuart, Guarné, Alba
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2691817/
https://ncbi.nlm.nih.gov/pubmed/19304745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp151
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