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p53-Independent Apoptosis Limits DNA Damage-Induced Aneuploidy
DNA damage or unprotected telomeres can trigger apoptosis via signaling pathways that directly sense abnormal DNA structures and activate the p53 transcription factor. We describe a p53-independent mechanism that acts in parallel to the canonical DNA damage response pathway in Drosophila to induce a...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Genetics Society of America
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2691752/ https://ncbi.nlm.nih.gov/pubmed/19364807 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.109.102327 |
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