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DDX3 regulates DNA damage-induced apoptosis and p53 stabilization

The DEAD box protein family member DDX3 was previously identified as an inhibitor of death receptor-mediated extrinsic apoptotic signaling. However, there had been no studies of the role of DDX3 in regulating the other major type of apoptosis, intrinsic apoptotic signaling, which was examined here....

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Detalhes bibliográficos
Main Authors: Sun, Mianen, Zhou, Tong, Jonasch, Eric, Jope, Richard S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3638797/
https://ncbi.nlm.nih.gov/pubmed/23470959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2013.02.026
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