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P55PIK Regulates P53-Dependent Apoptosis in Cancer Cells by Interacting with P53 DNA-Specific Domain

PURPOSE: Phosphatidylinositol 3-kinase (PI3K) plays an important role in tumorigenesis by cross-talking with several signaling pathways. p55PIK is a unique regulatory subunit of PI3K and contains an extra 24-residue N-terminal domain (N24). This study aimed to explore the interaction of p55PIK with...

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Bibliographische Detailangaben
Veröffentlicht in:Onco Targets Ther
Hauptverfasser: Li, Chaoxing, Li, Wenwen, Cheng, Xiyao, Zhang, Dapeng, Sun, Xiang, Zhou, Jingjing, Zhou, Yin, Huang, Yongqi, Xia, Xianmin, Ma, Qi, Su, Zhengding
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7292491/
https://ncbi.nlm.nih.gov/pubmed/32606738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S247200
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