Mutational Profile Of Advanced Primary and Metastatic Radioactive Iodine-Refractory Thyroid Cancers Reveals Distinct Pathogenetic Roles for BRAF, PIK3CA and AKT1

Patients with poorly differentiated (PDTC), anaplastic (ATC) and radioactive iodine-refractory (RAIR) differentiated thyroid cancers have a high mortality, particularly if positive on 18F-fluorodeoxyglucose-positron emission tomography (FDG-PET). To obtain comprehensive genetic information on advanc...

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Main Authors: Ricarte-Filho, Julio C., Ryder, Mabel, Chitale, Dhananjay A., Rivera, Michael, Heguy, Adriana, Ladanyi, Marc, Janakiraman, Manickam, Solit, David, Knauf, Jeffrey A., Tuttle, R. Michael, Ghossein, Ronald A., Fagin, James A.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2690720/
https://ncbi.nlm.nih.gov/pubmed/19487299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-0727
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