Evaluation of Romidepsin for Clinical Activity and Radioactive Iodine Reuptake in Radioactive Iodine–Refractory Thyroid Carcinoma

BACKGROUND: Historically, systemic therapy for radioactive iodine (RAI)–refractory thyroid cancer has been understudied. Available drugs have modest efficacy. Romidepsin is a histone deacetylase inhibitor with potent antitumor effects both in vitro and in vivo. In thyroid cancer cell lines, romideps...

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Detalhes bibliográficos
Main Authors: Sherman, Eric J., Su, Yungpo Bernard, Lyall, Ashima, Schöder, Heiko, Fury, Matthew G., Ghossein, Ronald A., Haque, Sofia, Lisa, Donna, Shaha, Ashok R., Tuttle, R. Michael, Pfister, David G.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2013
Assuntos:
Thyroid Cancer and Nodules
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3643228/
https://ncbi.nlm.nih.gov/pubmed/23186033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/thy.2012.0393
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