AGTR1 overexpression defines a subset of breast cancer and confers sensitivity to losartan, an AGTR1 antagonist

Breast cancer patients have benefited from the use of targeted therapies directed at specific molecular alterations. To identify additional opportunities for targeted therapy, we searched for genes with marked overexpression in subsets of tumors across a panel of breast cancer profiling studies comp...

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Bibliografiska uppgifter
Huvudupphovsmän: Rhodes, Daniel R., Ateeq, Bushra, Cao, Qi, Tomlins, Scott A., Mehra, Rohit, Laxman, Bharathi, Kalyana-Sundaram, Shanker, Lonigro, Robert J., Helgeson, Beth E., Bhojani, Mahaveer S., Rehemtulla, Alnawaz, Kleer, Celina G., Hayes, Daniel F., Lucas, Peter C., Varambally, Sooryanarayana, Chinnaiyan, Arul M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2009
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2689309/
https://ncbi.nlm.nih.gov/pubmed/19487683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0900351106
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