AGTR1 overexpression defines a subset of breast cancer and confers sensitivity to losartan, an AGTR1 antagonist

Breast cancer patients have benefited from the use of targeted therapies directed at specific molecular alterations. To identify additional opportunities for targeted therapy, we searched for genes with marked overexpression in subsets of tumors across a panel of breast cancer profiling studies comp...

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Autori principali: Rhodes, Daniel R., Ateeq, Bushra, Cao, Qi, Tomlins, Scott A., Mehra, Rohit, Laxman, Bharathi, Kalyana-Sundaram, Shanker, Lonigro, Robert J., Helgeson, Beth E., Bhojani, Mahaveer S., Rehemtulla, Alnawaz, Kleer, Celina G., Hayes, Daniel F., Lucas, Peter C., Varambally, Sooryanarayana, Chinnaiyan, Arul M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2009
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2689309/
https://ncbi.nlm.nih.gov/pubmed/19487683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0900351106
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