AGTR1 overexpression defines a subset of breast cancer and confers sensitivity to losartan, an AGTR1 antagonist

Breast cancer patients have benefited from the use of targeted therapies directed at specific molecular alterations. To identify additional opportunities for targeted therapy, we searched for genes with marked overexpression in subsets of tumors across a panel of breast cancer profiling studies comp...

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Detalles Bibliográficos
Autores principales: Rhodes, Daniel R., Ateeq, Bushra, Cao, Qi, Tomlins, Scott A., Mehra, Rohit, Laxman, Bharathi, Kalyana-Sundaram, Shanker, Lonigro, Robert J., Helgeson, Beth E., Bhojani, Mahaveer S., Rehemtulla, Alnawaz, Kleer, Celina G., Hayes, Daniel F., Lucas, Peter C., Varambally, Sooryanarayana, Chinnaiyan, Arul M.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2009
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2689309/
https://ncbi.nlm.nih.gov/pubmed/19487683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0900351106
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