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Mcl-1 is required for melanoma cell resistance to anoikis
Melanoma is a particularly aggressive tumor-type that exhibits a high level of resistance to apoptosis. The serine/threonine kinase, B-RAF, is mutated in 50–70% of melanomas and protects melanoma cells from anoikis, a form of apoptosis induced by lack of adhesion or adhesion to an inappropriate matr...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2689141/ https://ncbi.nlm.nih.gov/pubmed/19372583 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-08-0358 |
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