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FOXD3 is a mutant B-RAF-regulated inhibitor of G1/S progression in melanoma cells

The forkhead box transcription factor, FOXD3, is a stemness factor that prevents the production of melanocyte progenitors from the developing neural crest; however, its role in human cancers is not known. Transformation of melanocytes gives rise to melanoma. In two-thirds of melanomas, the serine/th...

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Detalhes bibliográficos
Main Authors: Abel, Ethan V., Aplin, Andrew E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2848900/
https://ncbi.nlm.nih.gov/pubmed/20332228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-3139
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