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Cyclin D3 Expression in Melanoma Cells Is Regulated by Adhesion-dependent Phosphatidylinositol 3-Kinase Signaling and Contributes to G(1)-S Progression

D-type cyclins regulate G(1) cell cycle progression by enhancing the activities of cyclin-dependent kinases (CDKs), and their expression is frequently altered in malignant cells. We and others have previously shown that cyclin D1 is up-regulated in melanoma cells through adhesion-independent MEK-ERK...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Biol Chem
Prif Awduron: Spofford, Laurie S., Abel, Ethan V., Boisvert-Adamo, Karen, Aplin, Andrew E.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2006
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4266577/
https://ncbi.nlm.nih.gov/pubmed/16815849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M600197200
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