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Caveolin-1 regulates Mcl-1 stability and anoikis in lung carcinoma cells

Both caveolin-1 (Cav-1) and Mcl-1 have been implicated in the regulation of cancer cell anoikis, but their relationship and underlying mechanisms of regulation are not known. The present study demonstrated for the first time that Cav-1 regulates Mcl-1 through protein-protein interaction and inhibits...

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Detalhes bibliográficos
Main Authors: Chunhacha, Preedakorn, Pongrakhananon, Varisa, Rojanasakul, Yon, Chanvorachote, Pithi
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3774262/
https://ncbi.nlm.nih.gov/pubmed/22277751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00318.2011
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