Prolonged Nitric Oxide Exposure Enhances Anoikis Resistance and Migration through Epithelial-Mesenchymal Transition and Caveolin-1 Upregulation

Nitric oxide (NO) in tumor microenvironment may have a significant impact on metastatic behaviors of cancer. Noncytotoxic doses of NO enhanced anoikis resistance and migration in lung cancer H23 cells via an increase in lamellipodia, epithelial-mesenchymal transition (EMT) markers including vimentin...

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Autores principales: Chanvorachote, Pithi, Pongrakhananon, Varisa, Chunhacha, Preedakorn
Formato: Artigo
Lenguaje:Inglês
Publicado: Hindawi Publishing Corporation 2014
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4055163/
https://ncbi.nlm.nih.gov/pubmed/24967418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/941359
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