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Caveolin-1 induces lamellipodia formation via an Akt-dependent pathway

BACKGROUND: The enhancement of migration is critical for facilitating cancer cell metastasis. METHOD: Lung cancer H23 cells were transfected with either a caveolin-1 (Cav-1) overexpression or shCav-1 plasmid and further subjected to cell migration assays and lamellipodia characterization. The regula...

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Detalhes bibliográficos
Main Authors: Chanvorachote, Pithi, Chunhacha, Preedakorn, Pongrakhananon, Varisa
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4064105/
https://ncbi.nlm.nih.gov/pubmed/24955034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2867-14-52
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