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p27 and Rb are on overlapping pathways suppressing tumorigenesis in mice

The commitment of cells to replicate and divide correlates with the activation of cyclin-dependent kinases and the inactivation of Rb, the product of the retinoblastoma tumor suppressor gene. Rb is a target of the cyclin-dependent kinases and, when phosphorylated, is inactivated. Biochemical studies...

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Détails bibliographiques
Auteurs principaux: Park, Michele S., Rosai, Juan, Nguyen, Hai T., Capodieci, Paola, Cordon-Cardo, Carlos, Koff, Andrew
Format: Artigo
Langue:Inglês
Publié: The National Academy of Sciences 1999
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC26890/
https://ncbi.nlm.nih.gov/pubmed/10339596
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