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RB-mediated suppression of spontaneous multiple neuroendocrine neoplasia and lung metastases in Rb(+/−) mice

Alterations in pathways mediated by retinoblastoma susceptibility gene (RB) product are among the most common in human cancer. Mice with a single copy of the Rb gene are shown to develop a syndrome of multiple neuroendocrine neoplasia. The earliest Rb-deficient atypical cells were identified in the...

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Hlavní autoři: Nikitin, Alexander Yu., Juárez-Pérez, María I., Li, Song, Huang, Leaf, Lee, Wen-Hwa
Médium: Artigo
Jazyk:Inglês
Vydáno: The National Academy of Sciences 1999
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC22395/
https://ncbi.nlm.nih.gov/pubmed/10097138
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