Human memory FOXP3(+) Tregs secrete IL-17 ex vivo and constitutively express the T(H)17 lineage-specific transcription factor RORγt

Recent studies have suggested a close relationship between CD4(+)FOXP3(+) regulatory T cells (Tregs) and proinflammatory IL-17-producing T helper cells (T(H)17) expressing the lineage-specific transcription factor RORγt. We report here the unexpected finding that human memory Tregs secrete IL-17 ex...

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Detalhes bibliográficos
Main Authors: Ayyoub, Maha, Deknuydt, Florence, Raimbaud, Isabelle, Dousset, Christelle, Leveque, Lucie, Bioley, Gilles, Valmori, Danila
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2688993/
https://ncbi.nlm.nih.gov/pubmed/19439651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0900621106
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