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A New Approach to Producing Functional Gα Subunits Yields the Activated and Deactivated Structures of Gα(12/13) Proteins
The oncogenic G(12/13) subfamily of heterotrimeric G proteins transduces extracellular signals that regulate the actin cytoskeleton, cell cycle progression, and gene transcription. Previously, structural analyses of fully-functional Gα(12/13) subunits have been hindered by insufficient amounts of ho...
Gorde:
| Egile Nagusiak: | , , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2006
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2688741/ https://ncbi.nlm.nih.gov/pubmed/16388592 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi051729t |
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