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Autophagic Elimination of Misfolded Procollagen Aggregates in the Endoplasmic Reticulum as a Means of Cell Protection

Type I collagen is a major component of the extracellular matrix, and mutations in the collagen gene cause several matrix-associated diseases. These mutant procollagens are misfolded and often aggregated in the endoplasmic reticulum (ER). Although the misfolded procollagens are potentially toxic to...

תיאור מלא

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מידע ביבליוגרפי
Main Authors: Ishida, Yoshihito, Yamamoto, Akitsugu, Kitamura, Akira, Lamandé, Shireen R., Yoshimori, Tamotsu, Bateman, John F., Kubota, Hiroshi, Nagata, Kazuhiro
פורמט: Artigo
שפה:Inglês
יצא לאור: The American Society for Cell Biology 2009
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2688553/
https://ncbi.nlm.nih.gov/pubmed/19357194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-11-1092
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