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Type I Collagen in Hsp47-null Cells Is Aggregated in Endoplasmic Reticulum and Deficient in N-Propeptide Processing and Fibrillogenesis

Heat-shock protein of 47 kDa (Hsp47) is a molecular chaperone that recognizes collagen triple helices in the endoplasmic reticulum (ER). Hsp47-knockout mouse embryos are deficient in the maturation of collagen types I and IV, and collagen triple helices formed in the absence of Hsp47 show increased...

詳細記述

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書誌詳細
主要な著者: Ishida, Yoshihito, Kubota, Hiroshi, Yamamoto, Akitsugu, Kitamura, Akira, Bächinger, Hans Peter, Nagata, Kazuhiro
フォーマット: Artigo
言語:Inglês
出版事項: The American Society for Cell Biology 2006
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1446091/
https://ncbi.nlm.nih.gov/pubmed/16525016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E05-11-1065
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