Activities of Ceftobiprole and Other Cephalosporins against Extracellular and Intracellular (THP-1 Macrophages and Keratinocytes) Forms of Methicillin-Susceptible and Methicillin-Resistant Staphylococcus aureus

Staphylococcus aureus is an opportunistic intracellular organism. Although they poorly accumulate in eukaryotic cells, β-lactams show activity against intracellular methicillin (meticillin)-susceptible S. aureus (MSSA) if the exposure times and the drug concentrations are sufficient. Intraphagocytic...

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Autores principales: Lemaire, Sandrine, Glupczynski, Youri, Duval, Valérie, Joris, Bernard, Tulkens, Paul M., Van Bambeke, Françoise
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2009
Materias:
Mechanisms of Action: Physiological Effects
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2687181/
https://ncbi.nlm.nih.gov/pubmed/19289525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01135-08
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