Role of Acidic pH in the Susceptibility of Intraphagocytic Methicillin-Resistant Staphylococcus aureus Strains to Meropenem and Cloxacillin

Early studies showed that methicillin-resistant Staphylococcus aureus (MRSA) strains are susceptible to β-lactams when they are exposed to pH ≤ 5.5 in broth. Because S. aureus survives in the phagolysosomes of macrophages, where the pH may be acidic, we have examined the susceptibility of MRSA ATCC...

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Bibliographische Detailangaben
Hauptverfasser: Lemaire, Sandrine, Van Bambeke, Françoise, Mingeot-Leclercq, Marie-Paule, Glupczynski, Youri, Tulkens, Paul M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2007
Schlagworte:
Susceptibility
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1855560/
https://ncbi.nlm.nih.gov/pubmed/17307986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01192-06
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