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Activation of the P2X7 ion channel by soluble and covalently bound ligands
The homotrimeric P2X7 purinergic receptor has sparked interest because of its capacity to sense adenosine triphosphate (ATP) and nicotinamide adenine dinucleotide (NAD) released from cells and to induce calcium signaling and cell death. Here, we examine the response of arginine mutants of P2X7 to so...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Springer Netherlands
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2686825/ https://ncbi.nlm.nih.gov/pubmed/19255877 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-009-9135-5 |
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