Activation of the P2X7 ion channel by soluble and covalently bound ligands

The homotrimeric P2X7 purinergic receptor has sparked interest because of its capacity to sense adenosine triphosphate (ATP) and nicotinamide adenine dinucleotide (NAD) released from cells and to induce calcium signaling and cell death. Here, we examine the response of arginine mutants of P2X7 to so...

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Hlavní autoři: Schwarz, Nicole, Fliegert, Ralf, Adriouch, Sahil, Seman, Michel, Guse, Andreas H., Haag, Friedrich, Koch-Nolte, Friedrich
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Netherlands 2009
Témata:
Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2686825/
https://ncbi.nlm.nih.gov/pubmed/19255877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-009-9135-5
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