Efficient construction of producer cell lines for a SIN lentiviral vector for SCID-X1 gene therapy by concatemeric array transfection

Retroviral vectors containing internal promoters, chromatin insulators, and self-inactivating (SIN) long terminal repeats (LTRs) may have significantly reduced genotoxicity relative to the conventional retroviral vectors used in recent, otherwise successful clinical trials. Large-scale production of...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Throm, Robert E., Ouma, Annastasia A., Zhou, Sheng, Chandrasekaran, Anantharaman, Lockey, Timothy, Greene, Michael, De Ravin, Suk See, Moayeri, Morvarid, Malech, Harry L., Sorrentino, Brian P., Gray, John T.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Hematology 2009
Materias:
Gene Therapy
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2686181/
https://ncbi.nlm.nih.gov/pubmed/19286997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-11-191049
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares