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Complement C1q Activates Tumor Suppressor WWOX to Induce Apoptosis in Prostate Cancer Cells

BACKGROUND: Tissue exudates contain low levels of serum complement proteins, and their regulatory effects on prostate cancer progression are largely unknown. We examined specific serum complement components in coordinating the activation of tumor suppressors p53 and WWOX (also named FOR or WOX1) and...

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Detalhes bibliográficos
Main Authors: Hong, Qunying, Sze, Chun-I, Lin, Sing-Ru, Lee, Ming-Hui, He, Ruei-Yu, Schultz, Lori, Chang, Jean-Yun, Chen, Shean-Jen, Boackle, Robert J., Hsu, Li-Jin, Chang, Nan-Shan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2685983/
https://ncbi.nlm.nih.gov/pubmed/19484134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005755
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