Complement C1q Activates Tumor Suppressor WWOX to Induce Apoptosis in Prostate Cancer Cells

BACKGROUND: Tissue exudates contain low levels of serum complement proteins, and their regulatory effects on prostate cancer progression are largely unknown. We examined specific serum complement components in coordinating the activation of tumor suppressors p53 and WWOX (also named FOR or WOX1) and...

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Bibliographic Details
Main Authors: Hong, Qunying, Sze, Chun-I, Lin, Sing-Ru, Lee, Ming-Hui, He, Ruei-Yu, Schultz, Lori, Chang, Jean-Yun, Chen, Shean-Jen, Boackle, Robert J., Hsu, Li-Jin, Chang, Nan-Shan
Format: Artigo
Language:Inglês
Published: Public Library of Science 2009
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2685983/
https://ncbi.nlm.nih.gov/pubmed/19484134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005755
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