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Identification of a Novel Zn(2+)-binding Domain in the Autosomal Recessive Juvenile Parkinson-related E3 Ligase Parkin
Missense mutations in park2, encoding the parkin protein, account for ∼50% of autosomal recessive juvenile Parkinson disease (ARJP) cases. Parkin belongs to the family of RBR (RING-between-RING) E3 ligases involved in the ubiquitin-mediated degradation and trafficking of proteins such as Pael-R and...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2685680/ https://ncbi.nlm.nih.gov/pubmed/19339245 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M808700200 |
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