Type II cGMP-dependent Protein Kinase Mediates Osteoblast Mechanotransduction

Continuous bone remodeling in response to mechanical loading is critical for skeletal integrity, and interstitial fluid flow is an important stimulus for osteoblast/osteocyte growth and differentiation. However, the biochemical signals mediating osteoblast anabolic responses to mechanical stimulatio...

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Autores principales: Rangaswami, Hema, Marathe, Nisha, Zhuang, Shunhui, Chen, Yongchang, Yeh, Jiunn-Chern, Frangos, John A., Boss, Gerry R., Pilz, Renate B.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2009
Materias:
Mechanisms of Signal Transduction
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2685661/
https://ncbi.nlm.nih.gov/pubmed/19282289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M806486200
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