ANG II infusion promotes abdominal aortic aneurysms independent of increased blood pressure in hypercholesterolemic mice

Infusion of ANG II in hyperlipidemic mice augments atherosclerosis and causes formation of abdominal aortic aneurysms (AAAs). The purpose of this study was to define the contribution of ANG II-induced hypertension to these vascular pathologies. Male apolipoprotein E (apoE)- and LDL receptor (LDLr)-d...

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Detalhes bibliográficos
Main Authors: Cassis, Lisa A., Gupte, Manisha, Thayer, Sarah, Zhang, Xuan, Charnigo, Richard, Howatt, Deborah A., Rateri, Debra L., Daugherty, Alan
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2009
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2685354/
https://ncbi.nlm.nih.gov/pubmed/19252100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00028.2009
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